Peptide Therapy · Physician-Led

Five protocols. One standard.

Recovery, growth hormone optimization, visceral-fat reduction, mitochondrial efficiency, and longevity — built from the literature, prescribed by a physician, sourced from licensed compounding pharmacies, and monitored on a defined schedule.

The Limitless Menu

Each peptide is a tool — and we use the right tool.

We do not run a one-size protocol. Every patient receives a peptide stack matched to a clinical question — recovery from injury, body composition stalled despite training, declining sleep architecture, or a longevity-focused floor on age-related decline.

Recovery · Tissue Repair

BPC-157 + TB-500

A complementary stack for tendon, ligament, and soft-tissue recovery. BPC-157 supports angiogenesis and gut-brain axis healing; TB-500 (Thymosin Beta-4) supports cell migration and fascial repair. Used together for stalled injuries and post-surgical recovery.

Best fit: athletes with chronic tendinopathy, post-op patients, anyone whose recovery has plateaued despite PT.

Read the protocol →
Growth Hormone · Sleep · Body Comp

Ipamorelin + CJC-1295

A growth-hormone secretagogue stack — Ipamorelin (selective GHRP) plus CJC-1295 No DAC (GHRH analog) — that prompts pulsatile, physiologic GH release without the supraphysiologic levels of exogenous HGH. Improvements in sleep depth, recovery, and lean mass over 12–16 weeks.

Best fit: men and women 35+ with declining sleep quality, slow recovery, or body composition stalled despite training.

Learn more →
Visceral Fat · Metabolic

Tesamorelin

A GHRH analog with the strongest evidence base for targeted reduction of visceral adipose tissue (VAT). Originally FDA-approved for HIV-associated lipodystrophy; now used clinically for metabolically active belly fat that resists diet and training.

Evidence Update — May 2026. A pooled meta-analysis of five randomized controlled trials reports a mean reduction of −27.7 cm² in visceral adipose tissue and an increase of +1.42 kg in lean body mass. More recent ART-era data show roughly 5% lower hepatic fat versus placebo, with concurrent improvements in triglycerides and CRP. A new 2026 randomized trial in patients on modern integrase-inhibitor (INSTI) regimens reports a median 16% VAT reduction at 12 months, with roughly two-thirds of treated patients meeting the clinical-responder threshold and no worsening of glycemic control. Fat quality improves independent of fat quantity — adipose-tissue density rises as VAT volume falls. Read the fat-quality analysis →

Best fit: patients on a GLP-1 plateau, "skinny visceral" lean-BMI patients with central adiposity, or MASLD/NAFLD with mild-to-moderate hepatic steatosis.

Read the protocol →
Mitochondrial · Cellular Energy

MOTS-c

A mitochondrial-derived peptide that activates AMPK — the same energy-sensing pathway hit by exercise and metformin. Supports mitochondrial efficiency, glucose handling, and exercise tolerance. The inside-the-cell complement to NAD+.

Best fit: patients with metabolic inflexibility, fatigue despite normal labs, or longevity-focused stacking.

Read the protocol →
Longevity · Cellular Repair

NAD+ Therapy

The Limitless signature — IV loading at 5 × 750 mg over two weeks, followed by subcutaneous maintenance of 100–200 mg daily or every other day. Restores the substrate that powers DNA repair, mitochondrial output, and sirtuin signaling.

Best fit: recommended on every Limitless protocol — adjusted for renal function and tolerability.

Read the protocol →
On Request · Sexual Health

PT-141

A melanocortin receptor agonist for low libido in both men and women, used selectively when desire is the primary concern and hormone optimization alone has not closed the gap. Prescribed only when specifically indicated — never by default.

Best fit: ask Dr. Hare during your visit if libido is a priority concern.

Discuss at consultation →
Educational · Cognitive Domain

Cognitive Peptides

Semax, Selank, and Dihexa target attention, anxiety, and synaptogenesis. The mechanisms are interesting; the human evidence is mixed. We publish our evaluation framework so you can think about them the way we do — under physician oversight, sourced through licensed 503A only.

Best fit: patients reading about nootropic peptides who want a physician's read before they buy from the gray market.

Read the framework →
How we run it

The Limitless standard on every protocol.

01

Source we can name

Every peptide originates from a state-licensed 503A pharmacy or FDA-registered 503B outsourcing facility. The pharmacy of origin is in your portal — we can name the source on request.

02

Prescription, not retail

A peptide is prescribed only after evaluation, lab review, and a documented clinical indication. We don't sell peptides at the front desk — they're prescribed and dispensed.

03

Defined monitoring

Each protocol carries a written monitoring plan: baseline labs, follow-up labs, symptom check-ins, stop criteria. The plan is in your portal before the first dose.

April 23, 2026 · FDA Reclassification
BPC-157, TB-500, CJC-1295, and Ipamorelin returned to compoundable status. Read our position →
Read the evidence · Limitless Research Library

The literature behind every peptide on this page.

Every Limitless protocol has a public, physician-authored research summary. Open the underlying evidence before you decide.

Peptides · Regulatory

BPC-157 at the FDA.

What the PCAC is actually evaluating on July 23, 2026 — and how Limitless prescribes BPC-157 inside the uncertainty.

Read summary →
Peptides · Metabolic

Tesamorelin 2026 meta-analysis.

Pooled five-trial result: −27.7 cm² VAT, +1.42 kg lean mass, with a cognitive-endpoint signal. What it does and does not support.

Read summary →
Longevity · Metabolic

NAD+ clinical evidence.

NR/NMN RCTs, IV pharmacokinetic data, and the precursor literature. What the 5×750 mg loading protocol actually rests on.

Read summary →
Peptides · Evidence

Hype vs. evidence.

A physician's response to the CNN and Topol skepticism. Three evidence tiers, six prescribing rules, and what we deliberately don't prescribe.

Read summary →
Daily Companion · Standing Protocol

One non-peptide we add to most adult-male protocols.

Limitless is a peptide-forward practice, but the best longevity protocols don't pretend a single class of molecules answers every question. Daily low-dose tadalafil sits alongside the peptide menu as our standing recommendation for endothelial, urinary, and erectile-health protection in men 35–75 with no contraindication.

Daily Optimization · Endothelial & Urinary

Tadalafil 5 mg daily

A long-acting PDE5 inhibitor used as a daily pathway-level medication, not an on-demand pill. Continuous nitric-oxide signaling supports endothelial function, lower urinary tract symptoms, erectile preservation, and an emerging cognitive-protection signal. FDA-approved for daily use in BPH and ED. Generic, inexpensive, well-tolerated.

Best fit: men 35–75 with vascular risk factors, BPH, post-prostatectomy, or on TRT — and no nitrate, hypotension, or specific ophthalmologic contraindication.

Read the protocol →
Common Questions

What patients ask before starting.

Q

Are peptides safe?

Compounded peptides are prescription therapeutics — not retail supplements. They carry real benefit and real risk. We mitigate risk with documented sourcing, evaluation, lab monitoring, and clear stop criteria. Anyone taking peptides without a physician's oversight is not in the safer lane.

Q

How long until I notice something?

Peptide-by-peptide. NAD+ patients often notice energy and clarity inside the first IV loading window. Recovery stacks (BPC/TB) typically show within 2–6 weeks. GH-secretagogue and Tesamorelin protocols are 12–16 week conversations.

Q

Are they covered by insurance?

Compounded peptides are typically not covered by insurance. We provide transparent self-pay pricing and itemized receipts. Many patients use HSA/FSA funds.

Q

Do I need to stay on them forever?

No protocol at Limitless is indefinite by default. Each carries a defined cycle, planned re-evaluation, and an exit point. We optimize, then we taper or stop and reassess.

The Limitless Way

Built for performance. Run like medicine.

A 30-minute consultation, a full lab panel, and a physician-built protocol — sourced, prescribed, and monitored to a documented standard.

Book a Consultation Read Compliance Statement
Compounded peptides described on this page are prescription therapeutics and are not FDA-approved drugs. Treatment decisions are made on an individual basis after evaluation by Joshua Hare, DO. Information provided is for educational purposes and does not constitute medical advice. Last reviewed May 3, 2026.